Molecular Genetics and Genomics
The GABRIEL Consortium at their final Annual Meeting in Davos, Switzerland, June 2010
Head - Professor Miriam Moffatt
The Molecular Genetics group is researching asthma, atopic dermatitis, the genetics of COPD, and the application of genomic technologies to the study of airway diseases.
We wish to identify all of the common genetic variants underlying asthma, eczema and COPD. This will be achieved by whole genome linkage disequilibrium mapping of large numbers of cases, controls, and families. We also wish to use genomics to discover the global picture of gene and protein expression by cells implicated in airway disease. These will include airway epithelial cells, macrophages, dendritic cells, and peripheral blood lymphocytes. The main tool for this research will be RNA microarray analyses.
GABRIEL
Professor Cookson, along with professor Erika von Mutius of Munich University, is also the Co-ordinator of the EU funded GABRIEL project, which involves 35 Partner institutions, and is investigating the genetic and environmental causes of asthma in the EU. http://www.gabriel-fp6.org
For information about GABRIEL please contact Dana Finch at the Project Office d.finch@imperial.ac.uk
Professors Cookson and Moffatt and members of their group, March 2010
