Professor Michael Levin

Paediatric Infectious Diseases Group

The paediatric infectious diseases group headed by Professor Michael Levin is applying genetic, genomic and proteomic methods to understanding of the immunopathogenesis of a number of life threatening infections in childhood.  Current programmes focus on meningococcal septicaemia and meningitis, childhood tuberculosis, Kawasaki disease, severe respiratory infection and H1N1 infection and severe malaria and septic shock in Africa.  The department has large scale DNA and RNA collections from patient cohorts with all of these diseases and is linking genomic and genetic approaches to understanding disease mechanisms in close collaboration with statistical and mathematical expertise in the Department of Mathematics and Statistical Genomics. 

PhD projects would be available on any of the diseases mentioned, focused on unravelling the immunopathogenesis and susceptibility.

The research group also has an interest in Mandelian defects causing susceptibility to unusual infection in childhood and has ongoing research interests in the interferon-gamma and IL12 pathway defects predisposing to mycobacterial infection.

Further information: http://www1.imperial.ac.uk/medicine/people/m.levin/

Contact Details
m.levin@imperial.ac.uk
Tel: +44 (0)20 7594 3760