Dr Felicity Gavins
Microcirculation
The main research interest of the Microcirculation group focuses on inflammation and the regulation of leukocyte trafficking in the microcirculation. In particular, the group uses the specialized techniques of intravital microscopy to study cellular interactions in the microvasculature (brain, mesentery, cremaster, lymph node) of animals with inflammation. This technique enables a qualitative and quantitative measurement of a variety of different events e.g. measurements of platelet-leukocyte-endothelial cell adhesion, endothelial surface expression of adhesion molecules in vascular beds, in vivo measurements of oxidant stress, and endothelial barrier function. The group has a special interest in sickle cell disease, thrombosis, stress and ischaemia reperfusion injury (including stroke and myocardial infarction).
The clinical specialty relevant to: Cardiology, neurology, and vascular surgery.
Further Information
Contact Details
f.gavins@imperial.ac.uk
