Faculty of Medicine

Selected Publications

  • Barnes MR; Huxley-Jones J; Maycox PR; Lennon M; Thornber A; Kelly F; Bates S; Taylor A; et al Reid J; Jones N; Schroeder J; Scorer CA; Davies C; Hagan JJ; Kew JN; Angelinetta C; Akbar T; Hirsch S; Mortimer AM; Barnes TR; de Belleroche J. (Aug 2011). Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia. J Neurosci Res. 89:1218-1227. DOI.
  • Reed L; de Belleroche JS. (Jun 2011). Investigating the causes of schizophrenia. Science in School. Summer 2011, 19:13-18.
  • Chen HJ; Anagnostou G; Chai A; Withers J; Morris A; Adhikaree J; Pennetta G; de Belleroche J. (Oct 2010). Characterisation of the properties of a novel mutation in VAPB in familial ALS. JOURNAL OF BIOLOGICAL CHEMISTRY. Epub:1-29. DOI.
  • Mitchell J; Paul P; Chen HJ; Morris A; Payling M; Falchi M; Habgood J; Panoutsou S; et alWinkler S; Tisato V; Hajitou A; Smith B; Vance C; Shaw C; Mazarakis ND; de Belleroche J. (20 Apr 2010). Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase. Proc Natl Acad Sci U S A. 107:7556-7561. DOI.
  • Maycox PR; Kelly F; Taylor A; Bates S; Reid J; Logendra R; Barnes MR; Larminie C; et alJones N; Lennon M; Davies C; Hagan JJ; Scorer CA; Angelinetta C; Akbar T; Hirsch S; Mortimer AM; Barnes TR; de Belleroche J. (Apr 2010). Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Mol Psychiatry. 15:442-443. DOI.
  • Bandopadhyay R; de Belleroche J. (Jan 2010). Pathogenesis of Parkinson's disease: emerging role of molecular chaperones. Trends Mol Med. 16:27-36. DOI.
  • van der Weerd L; Tariq Akbar M; Aron Badin R; Valentim LM; Thomas DL; Wells DJ; Latchman DS; Gadian DG; et alLythgoe MF; de Belleroche JS. (Apr 2010). Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. J Cereb Blood Flow Metab. 30:849-856. DOI.
  • Maycox PR; Kelly F; Taylor A; Bates S; Reid J; Logendra R; Barnes MR; Larminie C; et alJones N; Lennon M; Davies C; Hagan JJ; Scorer CA; Angelinetta C; Akbar MT; Hirsch S; Mortimer AM; Barnes TRE; de Belleroche J. (1 Dec 2009). Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function (vol 14, pg 1083, 2009). MOLECULAR PSYCHIATRY. 14:1146-1146. Author weblink DOI.
  • Rayner K; Sun J; Chen Y-X; McNulty M; Simard T; Zhao X; Wells DJ; de Belleroche J; et alO'Brien ER. (1 Nov 2009). Heat Shock Protein 27 Protects Against Atherogenesis via an Estrogen-Dependent Mechanism Role of Selective Estrogen Receptor Beta Modulation. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 29:1751-U90. Author weblink DOI.
  • Dai T; Patel-Chamberlin M; Natarajan R; Todorov I; Ma J; LaPage J; Phillips L; Nast CC; et alBecerra D; Chuang P; Tong L; de Belleroche J; Wells DJ; Wang Y; Adler SG. (Jul 2009). Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes. Endocrinology. 150:3031-3039. DOI.
  • Vance C; Rogelj B; Hortobagyi T; De Vos KJ; Nishimura AL; Sreedharan J; Hu X; Smith B; et alRuddy D; Wright P; Ganesalingam J; Williams KL; Tripathi V; Al-Saraj S; Al-Chalabi A; Leigh PN; Blair IP; Nicholson G; de Belleroche J; Gallo J-M; Miller CC; Shaw CE. (27 Feb 2009). Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6. SCIENCE. 323:1208-1211. Author weblink DOI.
  • Maycox PR; Kelly F; Taylor A; Bates S; Reid J; Logendra R; Barnes MR; Larminie C; et alJones N; Lennon M; Davies C; Hagan JJ; Scorer CA; Angelinetta C; Akbar MT; Hirsch S; Mortimer AM; Barnes TR; de Belleroche J. (Dec 2009). Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Mol Psychiatry. 14:1083-1094. DOI.
  • Chen SWC; Kim M; Kim M; Song JH; Park SW; Wells D; Brown K; de Belleroche J; et alD'Agati VD; Lee HT. (1 Mar 2009). Mice that overexpress human heat shock protein 27 have increased renal injury following ischemia reperfusion. KIDNEY INTERNATIONAL. 75:499-510. Author weblink DOI.
  • Benzel I; Kew JN; Viknaraja R; Kelly F; de Belleroche J; Hirsch S; Sanderson TH; Maycox PR. (2008). Investigation of G72 (DAOA) expression in the human brain. BMC Psychiatry. 8:94. DOI.
  • Mitchell J; Morris A; de Belleroche J. (15 Jan 2009). Thioredoxin reductase 1 haplotypes modify familial amyotrophic lateral sclerosis onset. Free Radic Biol Med. 46:202-211. DOI.
  • Anagnostou G; Akbar MT; Paul P; Angelinetta C; Steiner TJ; de Belleroche J. (Jun 2010). Vesicle associated membrane protein B (VAPB) is decreased in ALS spinal cord. Neurobiol Aging. 31:969-985. DOI.
  • Rayner K; Chen Y-X; McNulty M; Simard T; Zhao X; Wells DJ; de Belleroche J; O'Brien ER. (18 Jul 2008). Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A. CIRCULATION RESEARCH. 103:133-141. Author weblink DOI.
  • Sharp PS; Akbar MT; Bouri S; Senda A; Joshi K; Chen HJ; Latchman DS; Wells DJ; et alde Belleroche J. (Apr 2008). Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression. Neurobiol Dis. 30:42-55. DOI.
  • Sreedharan J; Blair IP; Tripathi VB; Hu X; Vance C; Rogelj B; Ackerley S; Durnall JC; et alWilliams KL; Buratti E; Baralle F; de Belleroche J; Mitchell JD; Leigh PN; Al-Chalabi A; Miller CC; Nicholson G; Shaw CE. (21 Mar 2008). TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science. 319:1668-1672. DOI.
  • Sharp P; Krishnan M; Pullar O; Navarrete R; Wells D; de Belleroche J. (Apr 2006). Heat shock protein 27 rescues motor neurons following nerve injury and preserves muscle function. Exp Neurol. 198:511-518. DOI.
  • Morita M; Al-Chalabi A; Andersen PM; Hosler B; Sapp P; Englund E; Mitchell JE; Habgood JJ; et alde Belleroche J; Xi J; Jongjaroenprasert W; Horvitz HR; Gunnarsson LG; Brown RH. (28 Mar 2006). A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia. Neurology. 66:839-844. DOI.
  • van der Weerd L; Lythgoe MF; Badin RA; Valentim LM; Akbar MT; de Belleroche JS; Latchman DS; Gadian DG. (Sep 2005). Neuroprotective effects of HSP70 overexpression after cerebral ischaemia--an MRI study. Exp Neurol. 195:257-266. DOI.

For a full list of publications please click here. 

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