Immune Response to Infection
Research in this area:
- Immune response to persistent viral infections
- Cell biology of human retroviral infections
- Lymphocyte dynamics
- Mathematical biology
Professor Charles R M Bangham
Selected publications:
- Spread of HTLV-1 between lymphocytes by virus-induced polarization of the cytoskeleton. Igakura T, Stinchcombe JC
- Low frequency of CD94/NKG2A-positive T lymphocytes in HTLV-1-associated myelopathy/tropical spastic paraparesis patients but not in asymptomatic carriers. Saito M, Braud VM, Goon P, Hanon E, Taylor GP, Saito A, Eiraku N, Tanaka Y, Usuku K, Weber JN, Osame M & Bangham CRM. Blood 2003; 102:577-584.
- The role of CTLs in persistent viral infection: cytolytic gene expression in CD8+ lymphocytes distinguishes between individuals with a high or low proviral load of HTLV-1. Vine AM, Heaps AG, Kaftantzi L, Mosley A, Asquith B, Witkover A, Thompson G, Saito M, Goon PKC, Carr L, Martinez-Murillo F, Taylor GP & Bangham CRM. J Immunol 2004; 173:5121-5129.
- A functional CD8+ cell assay reveals individual variation in CD8+ cell antiviral efficacy and explains differences in human T-lymphotropic virus type 1 proviral load. Asquith B, Mosley AJ, Barfield A, Marshall SE, Heaps A, Goon P, Hanon E, Tanaka Y, Taylor GP & Bangham CRM. J Gen Virol 2005; 86:1515-1523.
- Engagement of specific T cell surface molecules regulated cytoskeletal polarization in HTLV-1-infected lymphocytes. Barnard AL, Igakura T, Tanaka Y, Taylor GP & bangham CRM. Blood 2005 [Epub ahead of print].
