Publications 2011
Abaitua F, Daikoku T, Crump CM, Bolstad M, O'Hare P. A single mutation responsible for temperature sensitive entry and assembly defects in the VP1-2 protein of HSV. J Virol. 85: 2024-36, 2011
Bahar MW, Graham SC, Chen R, Cooray S, Smith GL, Stuart DI, Grimes JM.How vaccinia virus has evolved to subvert the host immune response. J Struct Biol. 175: 127-34, 2011.
Benfield CT, Mansur D, McCoy LE, Ferguson BJ, Bahar M, Oldring AP, Grimes JM, Stuart DI, Graham SC, Smith GL. Mapping the i{kappa}B kinase beta (ikk{beta})-binding interface of B14, a vaccinia virus inhibitor of IKK{beta}-mediated activation of nuclear factor kappa B. J Biol Chem 286: 20727-35, 2011.
Bhella D, Goodfellow IG. The cryo-EM structure of Feline Calicivirus bound to Junctional Adhesion Molecule A at 9 Angstroms resolution reveals receptor induced flexibility and two distinct conformational changes in the capsid protein VP1. J Virol. 85: 11381-90, 2011.
Bolstad M, Abaitua F, Crump CM, O'Hare P. Autocatalytic activity of the Ubiquitin Specific Protease domain of HSV-1 VP1-2. J Virol. 85: 8738-51, 2011
Bridge SH, Sharpe SA, Dennis MJ, Dowall SD, Getty B, Anson DS, Skinner MA, Stewart JP, Blanchard TJ. Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles. Virol J. 8: 429, 2011.
Brookes DW, Miah S, Lackenby A, Hartgroves L, Barclay WS. Pandemic H1N1 2009 influenza virus with the H275Y oseltamivir resistance neuraminidase mutation shows a small compromise in enzyme activity and viral fitness. J Antimicrob Chemother. 66: 466-70, 2011.
Cancian L, Bosshard R, Lucchesi W, Elgueta Karstegl C, Farrell PJ. C-terminal region of EBNA-2 determines the superior transforming ability of Type 1 Epstein-Barr virus by enhanced gene regulation of LMP-1 and CXCR7. PloS Pathogens 7: e1002164, 2011
Cancio-Lonches C, Yocupicio-Monroy M, Sandoval-Jaime C, Galvan-Mendoza I, Ureña L, Vashist S, Goodfellow I, Salas-Benito J, Gutiérrez-Escolano AL. Nucleolin interacts with the Feline calicivirus 3' untranslated region and the protease-polymerase NS6/7 protein, playing a role in virus replication. J Virol. 85: 8056-68, 2011.
Foeglein A, Loucaides EM, Mura M, Wise HM, Barclay WS, Digard P. Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase. J Gen Virol. 92: 1650-61, 2011.
Goodfellow I. The genome-linked protein VPg of vertebrate viruses - a multifaceted protein. Curr Opin Virol. 1: 355-62, 2011.
Gregorovic G, Bosshard R, Karstegl CE, White RE, Pattle S, Chiang AK, Dittrich-Breiholz O, Kracht M, Russ R, Farrell PJ. Cell gene expression correlating with EBER expression in Epstein-Barr virus infected lymphoblastoid cell lines. J Virol. 85: 3535-45, 2011.
Johnson BF, Kanatani Y, Fujii T, Saito T, Yokote H, Smith GL. Serological responses in humans to smallpox vaccine LC16m8. J Gen Virol. 92: 2405-10, 2011.
Lai IY-C, Farrell PJ and Kellam P. X-Box Binding Protein 1 induces the expression of lytic cycle transactivator of Kaposi sarcoma associated herpesvirus but not Epstein-Barr virus in coinfected Primary Effusion Lymphoma. J Gen Virol. 92: 421-31, 2011.
Loureiro S, Ren J, Phapugrangkul P, Colaco CA, Bailey CR, Shelton H, Molesti E, Temperton NJ, Barclay WS, Jones IM. Adjuvant free immunisation with Hemagglutinin-Fc fusion proteins as an approach to influenza vaccines. J Virol. 85: 3010-4, 2011
Maluquer de Motes C, Cooray S, Ren H, Almeida GM, McGourty K, Bahar MW, Stuart DI, Grimes JM, Graham SC, Smith GL. Inhibition of Apoptosis and NF-kB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence. PLoS Pathog. 2011 Dec;7(12):e1002430.
McFadden N, Bailey D, Carrara G, Benson A, Chaudhry Y, Shortland A, Heeney J, Yarovinsky F, Simmonds P, Macdonald A, Goodfellow I. Norovirus Regulation of the Innate Immune Response and Apoptosis Occurs via the Product of the Alternative Open Reading Frame 4. PLoS Pathog. 2011 Dec;7(12):e1002413.
Motes CM, Cooray S, Ren H, Almeida GM, McGourty K, Bahar MW, Stuart DI, Grimes JM, Graham SC, Smith GL. Inhibition of apoptosis and NF-kB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence. PLoS Pathog. 2011 Dec;7(12):e1002430.
Nor Rashid N, Yusof R, Watson RJ. Disruption of repressive p130/DREAM complexes by HPV16 E6/E7 oncoproteins is required for cell cycle progression in cervical cancer cells. J Gen Virol. 92: 2620-7, 2011.
Roberts KL, Shelton H, Scull MA, Pickles RJ, Barclay WS. Lack of transmission of a human influenza virus with avian receptor specificity between ferrets is not due to decreased virus shedding, but rather a lower infectivity in vivo. J Gen Virol. 92: 1822-31, 2011.
Salek-Ardakani S, Flynn R, Arens R, Yagita H, Smith GL, Borst J, Schoenberger SP, Croft M. The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice. J Clin Invest. 121: 296-307, 2011.
Shelton H, Ayora-Talavera G, Ren J, Loureiro S, Pickles RJ, Barclay WS, Jones IM. Receptor binding profiles of avian influenza virus hemagglutinin subtypes on human cells as a predictor of pandemic potential. J Virol. 85: 1875-80, 2011.
Subba-Reddy CV, Goodfellow I, Kao CC. VPg-Primed RNA Synthesis by Norovirus RNA-Dependent RNA Polymerases Using a Novel Cell-based Assay. J Virol. 85: 13027-37, 2011.
Unterholzner L, Sumner RP, Baran M, Ren H, Mansur DS, Bourke NM, Randow F, Smith GL, Bowie AG Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7. PLoS Pathog. 2011 Sep;7(9):e1002247.
van Doremalen N, Shelton H, Roberts KL, Jones IM, Pickles RJ, Thompson CI, Barclay WS.A Single Amino Acid in the HA of pH1N1 2009 Influenza Virus Affects Cell Tropism in Human Airway Epithelium, but Not Transmission in Ferrets. PLoS One. 2011;6(10):e25755.
Yángüez E, Castello A, Welnowska E, Carrasco L, Goodfellow I, Nieto A. Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation. Virology. 413: 93-102, 2011
Yee J, White RE, Anderton E, Allday MJ. Latent Epstein-Barr Virus Can Inhibit Apoptosis in B Cells by Blocking the Induction of NOXA Expression. PLoS One. 2011;6(12):e28506.
