Theory

Underpinning our research in infectious disease epidemiology are mathematical and statistical methods appropriate to the data collected and the research question under consideration. New methods based on underlying epidemiological theory become necessary as the quantity and scope of data available increases. We are interested in developing methods for analysing infectious disease data including immunological measurements, case reports, genetic sequences and outcomes from clinical trials and other intervention studies.

Selected Publications

Grassly NC and Fraser C 2008 Mathematical models of infectious disease transmission. Nat Rev Microbiol. 6: 477-487.

Grassly NC and Fraser C. 2006 Seasonal infectious disease epidemiology. Proc Roy Soc Lond B. 273: 2541-2550.

Grassly NC and Holmes EC. 1997. A likelihood method for the detection of selection and recombination using sequence data. Mol Biol Evol 14:239-247.