Dr John C Chambers

Publications


Journals

  • Gieger C; Radhakrishnan A; Cvejic A; Tang W; Porcu E; Pistis G; Serbanovic-Canic J; Elling U; et alGoodall AH; Labrune Y; Lopez LM; Mägi R; Meacham S; Okada Y; Pirastu N; Sorice R; Teumer A; Voss K; Zhang W; Ramirez-Solis R; Bis JC; Ellinghaus D; Gögele M; Hottenga JJ; Langenberg C; Kovacs P; O'Reilly PF; Shin SY; Esko T; Hartiala J; Kanoni S; Murgia F; Parsa A; Stephens J; van der Harst P; Ellen van der Schoot C; Allayee H; Attwood A; Balkau B; Bastardot F; Basu S; Baumeister SE; Biino G; Bomba L; Bonnefond A; Cambien F; Chambers JC; Cucca F; D'Adamo P; Davies G; de Boer RA; de Geus EJ; Döring A; Elliott P; Erdmann J; Evans DM; Falchi M; Feng W; Folsom AR; Frazer IH; Gibson QD; Glazer NL; Hammond C; Hartikainen AL; Heckbert SR; Hengstenberg C; Hersch M; Illig T; Loos RJ; Jolley J; Tee Khaw K; Kühnel B; Kyrtsonis MC; Lagou V; Lloyd-Jones H; Lumley T; Mangino M; Maschio A; Mateo Leach I; McKnight B; Memari Y; Mitchell BD; Montgomery GW; Nakamura Y; Nauck M; Navis G; Nöthlings U; Nolte IM; Porteous DJ; Pouta A; Pramstaller PP; Pullat J; Ring SM; Rotter JI; Ruggiero D; Ruokonen A; Sala C; Samani NJ; Sambrook J; Schlessinger D; Schreiber S; Schunkert H; Scott J; Smith NL; Snieder H; Starr JM; Stumvoll M; Takahashi A; Tang WH; Taylor K; Tenesa A; Lay Thein S; Tönjes A; Uda M; Ulivi S; van Veldhuisen DJ; Visscher PM; Völker U; Wichmann HE; Wiggins KL; Willemsen G; Yang TP; Hua Zhao J; Zitting P; Bradley JR; Dedoussis GV; Gasparini P; Hazen SL; Metspalu A; Pirastu M; Shuldiner AR; Joost van Pelt L; Zwaginga JJ; Boomsma DI; Deary IJ; Franke A; Froguel P; Ganesh SK; Jarvelin MR; Martin NG; Meisinger C; Psaty BM; Spector TD; Wareham NJ; Akkerman JW; Ciullo M; Deloukas P; Greinacher A; Jupe S; Kamatani N; Khadake J; Kooner JS; Penninger J; Prokopenko I; Stemple D; Toniolo D; Wernisch L; Sanna S; Hicks AA; Rendon A; Ferreira MA; Ouwehand WH; Soranzo N. (8 Dec 2011). New gene functions in megakaryopoiesis and platelet formation. Nature. 480:201-208. DOI.
  • Hoggart CJ; O'Reilly PF; Kaakinen M; Zhang W; Chambers JC; Kooner JS; Coin LJ; Jarvelin MR. (17 Nov 2011). Fine-scale Estimation of Location of Birth from Genome-wide SNP Data. Genetics. DOI.
  • Chambers JC; Zhang W; Sehmi J; Li X; Wass MN; Van der Harst P; Holm H; Sanna S; et alKavousi M; Baumeister SE; Coin LJ; Deng G; Gieger C; Heard-Costa NL; Hottenga JJ; Kühnel B; Kumar V; Lagou V; Liang L; Luan J; Vidal PM; Mateo Leach I; O'Reilly PF; Peden JF; Rahmioglu N; Soininen P; Speliotes EK; Yuan X; Thorleifsson G; Alizadeh BZ; Atwood LD; Borecki IB; Brown MJ; Charoen P; Cucca F; Das D; de Geus EJ; Dixon AL; Döring A; Ehret G; Eyjolfsson GI; Farrall M; Forouhi NG; Friedrich N; Goessling W; Gudbjartsson DF; Harris TB; Hartikainen AL; Heath S; Hirschfield GM; Hofman A; Homuth G; Hyppönen E; Janssen HL; Johnson T; Kangas AJ; Kema IP; Kühn JP; Lai S; Lathrop M; Lerch MM; Li Y; Liang TJ; Lin JP; Loos RJ; Martin NG; Moffatt MF; Montgomery GW; Munroe PB; Musunuru K; Nakamura Y; O'Donnell CJ; Olafsson I; Penninx BW; Pouta A; Prins BP; Prokopenko I; Puls R; Ruokonen A; Savolainen MJ; Schlessinger D; Schouten JN; Seedorf U; Sen-Chowdhry S; Siminovitch KA; Smit JH; Spector TD; Tan W; Teslovich TM; Tukiainen T; Uitterlinden AG; Van der Klauw MM; Vasan RS; Wallace C; Wallaschofski H; Wichmann HE; Willemsen G; Würtz P; Xu C; Yerges-Armstrong LM; Alcohol Genome-wide Association (AlcGen) Consortium; Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study; Genetic Investigation of Anthropometric Traits (GIANT) Consortium; Global Lipids Genetics Consortium; Genetics of Liver Disease (GOLD) Consortium; International Consortium for Blood Pressure (ICBP-GWAS); Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC); Abecasis GR; Ahmadi KR; Boomsma DI; Caulfield M; Cookson WO; van Duijn CM; Froguel P; Matsuda K; McCarthy MI; Meisinger C; Mooser V; Pietiläinen KH; Schumann G; Snieder H; Sternberg MJ; Stolk RP; Thomas HC; Thorsteinsdottir U; Uda M; Waeber G; Wareham NJ; Waterworth DM; Watkins H; Whitfield JB; Witteman JC; Wolffenbuttel BH; Fox CS; Ala-Korpela M; Stefansson K; Vollenweider P; Völzke H; Schadt EE; Scott J; Järvelin MR; Elliott P; Kooner JS. (Nov 2011). Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 43:1131-1138. DOI.
  • International Consortium for Blood Pressure Genome-Wide Association Studies; Ehret GB; Munroe PB; Rice KM; Bochud M; Johnson AD; Chasman DI; Smith AV; et alTobin MD; Verwoert GC; Hwang SJ; Pihur V; Vollenweider P; O'Reilly PF; Amin N; Bragg-Gresham JL; Teumer A; Glazer NL; Launer L; Zhao JH; Aulchenko Y; Heath S; Sõber S; Parsa A; Luan J; Arora P; Dehghan A; Zhang F; Lucas G; Hicks AA; Jackson AU; Peden JF; Tanaka T; Wild SH; Rudan I; Igl W; Milaneschi Y; Parker AN; Fava C; Chambers JC; Fox ER; Kumari M; Go MJ; van der Harst P; Kao WH; Sjögren M; Vinay DG; Alexander M; Tabara Y; Shaw-Hawkins S; Whincup PH; Liu Y; Shi G; Kuusisto J; Tayo B; Seielstad M; Sim X; Nguyen KD; Lehtimäki T; Matullo G; Wu Y; Gaunt TR; Onland-Moret NC; Cooper MN; Platou CG; Org E; Hardy R; Dahgam S; Palmen J; Vitart V; Braund PS; Kuznetsova T; Uiterwaal CS; Adeyemo A; Palmas W; Campbell H; Ludwig B; Tomaszewski M; Tzoulaki I; Palmer ND; CARDIoGRAM consortium; CKDGen Consortium; KidneyGen Consortium; EchoGen consortium; CHARGE-HF consortium; Aspelund T; Garcia M; Chang YP; O'Connell JR; Steinle NI; Grobbee DE; Arking DE; Kardia SL; Morrison AC; Hernandez D; Najjar S; McArdle WL; Hadley D; Brown MJ; Connell JM; Hingorani AD; Day IN; Lawlor DA; Beilby JP; Lawrence RW; Clarke R; Hopewell JC; Ongen H; Dreisbach AW; Li Y; Young JH; Bis JC; Kähönen M; Viikari J; Adair LS; Lee NR; Chen MH; Olden M; Pattaro C; Bolton JA; Köttgen A; Bergmann S; Mooser V; Chaturvedi N; Frayling TM; Islam M; Jafar TH; Erdmann J; Kulkarni SR; Bornstein SR; Grässler J; Groop L; Voight BF; Kettunen J; Howard P; Taylor A; Guarrera S; Ricceri F; Emilsson V; Plump A; Barroso I; Khaw KT; Weder AB; Hunt SC; Sun YV; Bergman RN; Collins FS; Bonnycastle LL; Scott LJ; Stringham HM; Peltonen L; Perola M; Vartiainen E; Brand SM; Staessen JA; Wang TJ; Burton PR; Artigas MS; Dong Y; Snieder H; Wang X; Zhu H; Lohman KK; Rudock ME; Heckbert SR; Smith NL; Wiggins KL; Doumatey A; Shriner D; Veldre G; Viigimaa M; Kinra S; Prabhakaran D; Tripathy V; Langefeld CD; Rosengren A; Thelle DS; Corsi AM; Singleton A; Forrester T; Hilton G; McKenzie CA; Salako T; Iwai N; Kita Y; Ogihara T; Ohkubo T; Okamura T; Ueshima H; Umemura S; Eyheramendy S; Meitinger T; Wichmann HE; Cho YS; Kim HL; Lee JY; Scott J; Sehmi JS; Zhang W; Hedblad B; Nilsson P; Smith GD; Wong A; Narisu N; Stančáková A; Raffel LJ; Yao J; Kathiresan S; O'Donnell CJ; Schwartz SM; Ikram MA; Longstreth WT; Mosley TH; Seshadri S; Shrine NR; Wain LV; Morken MA; Swift AJ; Laitinen J; Prokopenko I; Zitting P; Cooper JA; Humphries SE; Danesh J; Rasheed A; Goel A; Hamsten A; Watkins H; Bakker SJ; van Gilst WH; Janipalli CS; Mani KR; Yajnik CS; Hofman A; Mattace-Raso FU; Oostra BA; Demirkan A; Isaacs A; Rivadeneira F; Lakatta EG; Orru M; Scuteri A; Ala-Korpela M; Kangas AJ; Lyytikäinen LP; Soininen P; Tukiainen T; Würtz P; Ong RT; Dörr M; Kroemer HK; Völker U; Völzke H; Galan P; Hercberg S; Lathrop M; Zelenika D; Deloukas P; Mangino M; Spector TD; Zhai G; Meschia JF; Nalls MA; Sharma P; Terzic J; Kumar MV; Denniff M; Zukowska-Szczechowska E; Wagenknecht LE; Fowkes FG; Charchar FJ; Schwarz PE; Hayward C; Guo X; Rotimi C; Bots ML; Brand E; Samani NJ; Polasek O; Talmud PJ; Nyberg F; Kuh D; Laan M; Hveem K; Palmer LJ; van der Schouw YT; Casas JP; Mohlke KL; Vineis P; Raitakari O; Ganesh SK; Wong TY; Tai ES; Cooper RS; Laakso M; Rao DC; Harris TB; Morris RW; Dominiczak AF; Kivimaki M; Marmot MG; Miki T; Saleheen D; Chandak GR; Coresh J; Navis G; Salomaa V; Han BG; Zhu X; Kooner JS; Melander O; Ridker PM; Bandinelli S; Gyllensten UB; Wright AF; Wilson JF; Ferrucci L; Farrall M; Tuomilehto J; Pramstaller PP; Elosua R; Soranzo N; Sijbrands EJ; Altshuler D; Loos RJ; Shuldiner AR; Gieger C; Meneton P; Uitterlinden AG; Wareham NJ; Gudnason V; Rotter JI; Rettig R; Uda M; Strachan DP; Witteman JC; Hartikainen AL; Beckmann JS; Boerwinkle E; Vasan RS; Boehnke M; Larson MG; Järvelin MR; Psaty BM; Abecasis GR; Chakravarti A; Elliott P; van Duijn CM; Newton-Cheh C; Levy D; Caulfield MJ; Johnson T; Tang H; Knowles J; Hlatky M; Fortmann S; Assimes TL; Quertermous T; Go A; Iribarren C; Absher D; Risch N; Myers R; Sidney S; Ziegler A; Schillert A; Bickel C; Sinning C; Rupprecht HJ; Lackner K; Wild P; Schnabel R; Blankenberg S; Zeller T; Münzel T; Perret C; Cambien F; Tiret L; Nicaud V; Proust C; Dehghan A; Hofman A; Uitterlinden A; van Duijn C; Levy D; Whitteman J; Cupples LA; Demissie-Banjaw S; Ramachandran V; Smith A; Gudnason V; Boerwinkle E; Folsom A; Morrison A; Psaty BM; Chen IY; Rotter JI; Bis J; Volcik K; Rice K; Taylor KD; Marciante K; Smith N; Glazer N; Heckbert S; Harris T; Lumley T; Kong A; Thorleifsson G; Thorgeirsson G; Holm H; Gulcher JR; Stefansson K; Andersen K; Gretarsdottir S; Thorsteinsdottir U; Preuss M; Schreiber S; Meitinger T; König IR; Lieb W; Hengstenberg C; Schunkert H; Erdmann J; Fischer M; Grosshennig A; Medack A; Stark K; Linsel-Nitschke P; Bruse P; Aherrahrou Z; Peters A; Loley C; Willenborg C; Nahrstedt J; Freyer J; Gulde S; Doering A; Meisinger C; Wichmann HE; Klopp N; Illig T; Meinitzer A; Tomaschitz A; Halperin E; Dobnig H; Scharnagl H; Kleber M; Laaksonen R; Pilz S; Grammer TB; Stojakovic T; Renner W; März W; Böhm BO; Winkelmann BR; Winkler K; Hoffmann MM; O'Donnell CJ; Voight BF; Altshuler D; Siscovick DS; Musunuru K; Peltonen L; Barbalic M; Melander O; Elosua R; Kathiresan S; Schwartz SM; Salomaa V; Guiducci C; Burtt N; Gabriel SB; Stewart AF; Wells GA; Chen L; Jarinova O; Roberts R; McPherson R; Dandona S; Pichard AD; Rader DJ; Devaney J; Lindsay JM; Kent KM; Qu L; Satler L; Burnett MS; Li M; Reilly MP; Wilensky R; Waksman R; Epstein S; Matthai W; Knouff CW; Waterworth DM; Hakonarson HH; Walker MC; Mooser V; Hall AS; Balmforth AJ; Wright BJ; Nelson C; Thompson JR; Samani NJ; Braund PS; Ball SG; Smith NL; Felix JF; Morrison AC; Demissie S; Glazer NL; Loehr LR; Cupples LA; Dehghan A; Lumley T; Rosamond WD; Lieb W; Rivadeneira F; Bis JC; Folsom AR; Benjamin E; Aulchenko YS; Haritunians T; Couper D; Murabito J; Wang YA; Stricker BH; Gottdiener JS; Chang PP; Wang TJ; Rice KM; Hofman A; Heckbert SR; Fox ER; O'Donnell CJ; Uitterlinden AG; Rotter JI; Willerson JT; Levy D; van Duijn CM; Psaty BM; Witteman JC; Boerwinkle E; Vasan RS; Köttgen A; Pattaro C; Böger CA; Fuchsberger C; Olden M; Glazer NL; Parsa A; Gao X; Yang Q; Smith AV; O'Connell JR; Li M; Schmidt H; Tanaka T; Isaacs A; Ketkar S; Hwang SJ; Johnson AD; Dehghan A; Teumer A; Paré G; Atkinson EJ; Zeller T; Lohman K; Cornelis MC; Probst-Hensch NM; Kronenberg F; Tönjes A; Hayward C; Aspelund T; Eiriksdottir G; Launer LJ; Harris TB; Rampersaud E; Mitchell BD; Arking DE; Boerwinkle E; Struchalin M; Cavalieri M; Singleton A; Giallauria F; Metter J; de Boer J; Haritunians T; Lumley T; Siscovick D; Psaty BM; Zillikens MC; Oostra BA; Feitosa M; Province M; de Andrade M; Turner ST; Schillert A; Ziegler A; Wild PS; Schnabel RB; Wilde S; Munzel TF; Leak TS; Illig T; Klopp N; Meisinger C; Wichmann HE; Koenig W; Zgaga L; Zemunik T; Kolcic I; Minelli C; Hu FB; Johansson A; Igl W; Zaboli G; Wild SH; Wright AF; Campbell H; Ellinghaus D; Schreiber S; Aulchenko YS; Felix JF; Rivadeneira F; Uitterlinden AG; Hofman A; Imboden M; Nitsch D; Brandstätter A; Kollerits B; Kedenko L; Mägi R; Stumvoll M; Kovacs P; Boban M; Campbell S; Endlich K; Völzke H; Kroemer HK; Nauck M; Völker U; Polasek O; Vitart V; Badola S; Parker AN; Ridker PM; Kardia SL; Blankenberg S; Liu Y; Curhan GC; Franke A; Rochat T; Paulweber B; Prokopenko I; Wang W; Gudnason V; Shuldiner AR; Coresh J; Schmidt R; Ferrucci L; Shlipak MG; van Duijn CM; Borecki I; Krämer BK; Rudan I; Gyllensten U; Wilson JF; Witteman JC; Pramstaller PP; Rettig R; Hastie N; Chasman DI; Kao WH; Heid IM; Fox CS; Vasan RS; Glazer NL; Felix JF; Lieb W; Wild PS; Felix SB; Watzinger N; Larson MG; Smith NL; Dehghan A; Grosshennig A; Schillert A; Teumer A; Schmidt R; Kathiresan S; Lumley T; Aulchenko YS; König IR; Zeller T; Homuth G; Struchalin M; Aragam J; Bis JC; Rivadeneira F; Erdmann J; Schnabel RB; Dörr M; Zweiker R; Lind L; Rodeheffer RJ; Greiser KH; Levy D; Haritunians T; Deckers JW; Stritzke J; Lackner KJ; Völker U; Ingelsson E; Kullo I; Haerting J; O'Donnell CJ; Heckbert SR; Stricker BH; Ziegler A; Reffelmann T; Redfield MM; Werdan K; Mitchell GF; Rice K; Arnett DK; Hofman A; Gottdiener JS; Uitterlinden AG; Meitinger T; Blettner M; Friedrich N; Wang TJ; Psaty BM; van Duijn CM; Wichmann HE; Munzel TF; Kroemer HK; Benjamin EJ; Rotter JI; Witteman JC; Schunkert H; Schmidt H; Völzke H; Blankenberg S; Chambers JC; Zhang W; Lord GM; van der Harst P; Lawlor DA; Sehmi JS; Gale DP; Wass MN; Ahmadi KR; Bakker SJ; Beckmann J; Bilo HJ; Bochud M; Brown MJ; Caulfield MJ; Connell JM; Cook HT; Cotlarciuc I; Davey Smith G; de Silva R; Deng G; Devuyst O; Dikkeschei LD; Dimkovic N; Dockrell M; Dominiczak A; Ebrahim S; Eggermann T; Farrall M; Ferrucci L; Floege J; Forouhi NG; Gansevoort RT; Han X; Hedblad B; Homan van der Heide JJ; Hepkema BG; Hernandez-Fuentes M; Hypponen E; Johnson T; de Jong PE; Kleefstra N; Lagou V; Lapsley M; Li Y; Loos RJ; Luan J; Luttropp K; Maréchal C; Melander O; Munroe PB; Nordfors L; Parsa A; Peltonen L; Penninx BW; Perucha E; Pouta A; Prokopenko I; Roderick PJ; Ruokonen A; Samani NJ; Sanna S; Schalling M; Schlessinger D; Schlieper G; Seelen MA; Shuldiner AR; Sjögren M; Smit JH; Snieder H; Soranzo N; Spector TD; Stenvinkel P; Sternberg MJ; Swaminathan R; Tanaka T; Ubink-Veltmaat LJ; Uda M; Vollenweider P; Wallace C; Waterworth D; Zerres K; Waeber G; Wareham NJ; Maxwell PH; McCarthy MI; Jarvelin MR; Mooser V; Abecasis GR; Lightstone L; Scott J; Navis G; Elliott P; Kooner JS. (6 Oct 2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 478:103-109. DOI.
  • Butterworth AS; Braund PS; Farrall M; Hardwick RJ; Saleheen D; Peden JF; Soranzo N; Chambers JC; et alSivapalaratnam S; Kleber ME; Keating B; Qasim A; Klopp N; Erdmann J; Assimes TL; Ball SG; Balmforth AJ; Barnes TA; Basart H; Baumert J; Bezzina CR; Boerwinkle E; Boehm BO; Brocheton J; Bugert P; Cambien F; Clarke R; Codd V; Collins R; Couper D; Cupples LA; de Jong JS; Diemert P; Ejebe K; Elbers CC; Elliott P; Fornage M; Franzosi MG; Frossard P; Garner S; Goel A; Goodall AH; Hengstenberg C; Hunt SE; Kastelein JJP; Klungel OH; Kluter H; Koch K; Konig IR; Kooner AS; Laaksonen R; Lathrop M; Li MY; Liu K; McPherson R; Musameh MD; Musani S; Nelson CP; O'Donnell CJ; Ongen H; Papanicolaou G; Peters A; Peters BJM; Potter S; Psaty BM; Qu LM; Rader DJ; Rasheed A; Rice C; Scott J; Seedorf U; Sehmi JS; Sotoodehnia N; Stark K; Stephens J; van der Schoot CE; van der Schouw YT; Thorsteinsdottir U; Tomaszewski M; van der Harst P; Vasan RS; Wilde AAM; Willenborg C; Winkelmann BR; Zaidi M; Zhang WH; Ziegler A; de Bakker PIW; Koenig W; Marz W; Trip MD; Reilly MP; Kathiresan S; Schunkert H; Hamsten A; Hall AS; Kooner JS; Thompson SG; Thompson JR; Deloukas P; Ouwehand WH; Watkins H; Danesh J; Samani NJ; IBC 50K CAD Consortium. (Sep 2011). Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease. PLOS GENET. 7. DOI.
  • Wain LV; Verwoert GC; O'Reilly PF; Shi G; Johnson T; Johnson AD; Bochud M; Rice KM; et alHenneman P; Smith AV; Ehret GB; Amin N; Larson MG; Mooser V; Hadley D; Dörr M; Bis JC; Aspelund T; Esko T; Janssens AC; Zhao JH; Heath S; Laan M; Fu J; Pistis G; Luan J; Arora P; Lucas G; Pirastu N; Pichler I; Jackson AU; Webster RJ; Zhang F; Peden JF; Schmidt H; Tanaka T; Campbell H; Igl W; Milaneschi Y; Hottenga JJ; Vitart V; Chasman DI; Trompet S; Bragg-Gresham JL; Alizadeh BZ; Chambers JC; Guo X; Lehtimäki T; Kühnel B; Lopez LM; Polašek O; Boban M; Nelson CP; Morrison AC; Pihur V; Ganesh SK; Hofman A; Kundu S; Mattace-Raso FU; Rivadeneira F; Sijbrands EJ; Uitterlinden AG; Hwang SJ; Vasan RS; Wang TJ; Bergmann S; Vollenweider P; Waeber G; Laitinen J; Pouta A; Zitting P; McArdle WL; Kroemer HK; Völker U; Völzke H; Glazer NL; Taylor KD; Harris TB; Alavere H; Haller T; Keis A; Tammesoo ML; Aulchenko Y; Barroso I; Khaw KT; Galan P; Hercberg S; Lathrop M; Eyheramendy S; Org E; Sõber S; Lu X; Nolte IM; Penninx BW; Corre T; Masciullo C; Sala C; Groop L; Voight BF; Melander O; O'Donnell CJ; Salomaa V; d'Adamo AP; Fabretto A; Faletra F; Ulivi S; Del Greco M F; Facheris M; Collins FS; Bergman RN; Beilby JP; Hung J; Musk AW; Mangino M; Shin SY; Soranzo N; Watkins H; Goel A; Hamsten A; Gider P; Loitfelder M; Zeginigg M; Hernandez D; Najjar SS; Navarro P; Wild SH; Corsi AM; Singleton A; de Geus EJ; Willemsen G; Parker AN; Rose LM; Buckley B; Stott D; Orru M; Uda M; van der Klauw MM; Zhang W; Li X; Scott J; Chen YD; Burke GL; Kähönen M; Viikari J; Döring A; Meitinger T; Davies G; Starr JM; Emilsson V; Plump A; Lindeman JH; Hoen PA; König IR; Felix JF; Clarke R; Hopewell JC; Ongen H; Breteler M; Debette S; Destefano AL; Fornage M; Mitchell GF; Smith NL; Holm H; Stefansson K; Thorleifsson G; Thorsteinsdottir U; Samani NJ; Preuss M; Rudan I; Hayward C; Deary IJ; Wichmann HE; Raitakari OT; Palmas W; Kooner JS; Stolk RP; Jukema JW; Wright AF; Boomsma DI; Bandinelli S; Gyllensten UB; Wilson JF; Ferrucci L; Schmidt R; Farrall M; Spector TD; Palmer LJ; Tuomilehto J; Pfeufer A; Gasparini P; Siscovick D; Altshuler D; Loos RJ; Toniolo D; Snieder H; Gieger C; Meneton P; Wareham NJ; Oostra BA; Metspalu A; Launer L; Rettig R; Strachan DP; Beckmann JS; Witteman JC; Erdmann J; van Dijk KW; Boerwinkle E; Boehnke M; Ridker PM; Jarvelin MR; Chakravarti A; Abecasis GR; Gudnason V; Newton-Cheh C; Levy D; Munroe PB; Psaty BM; Caulfield MJ; Rao DC; Tobin MD; Elliott P; van Duijn CM; LifeLines Cohort Study; EchoGen consortium; AortaGen Consortium; CHARGE Consortium Heart Failure Working Group; KidneyGen consortium; CKDGen consortium; Cardiogenics consortium; CardioGram. (Oct 2011). Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 43:1005-1011. DOI.
  • Chahal NS; Lim TK; Jain P; Chambers JC; Kooner JS; Senior R. (Sep 2011). Does subclinical atherosclerosis burden identify the increased risk of cardiovascular disease mortality among United Kingdom Indian Asians? A population study. Am Heart J. 162:460-466. DOI.
  • Kooner JS; Saleheen D; Sim X; Sehmi J; Zhang W; Frossard P; Been LF; Chia KS; et alDimas AS; Hassanali N; Jafar T; Jowett JB; Li X; Radha V; Rees SD; Takeuchi F; Young R; Aung T; Basit A; Chidambaram M; Das D; Grundberg E; Hedman AK; Hydrie ZI; Islam M; Khor CC; Kowlessur S; Kristensen MM; Liju S; Lim WY; Matthews DR; Liu J; Morris AP; Nica AC; Pinidiyapathirage JM; Prokopenko I; Rasheed A; Samuel M; Shah N; Shera AS; Small KS; Suo C; Wickremasinghe AR; Wong TY; Yang M; Zhang F; DIAGRAM; MuTHER; Abecasis GR; Barnett AH; Caulfield M; Deloukas P; Frayling TM; Froguel P; Kato N; Katulanda P; Kelly MA; Liang J; Mohan V; Sanghera DK; Scott J; Seielstad M; Zimmet PZ; Elliott P; Teo YY; McCarthy MI; Danesh J; Tai ES; Chambers JC. (Oct 2011). Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet. 43:984-989. DOI.
  • Kilpeläinen TO; Zillikens MC; Stančákova A; Finucane FM; Ried JS; Langenberg C; Zhang W; Beckmann JS; et alLuan J; Vandenput L; Styrkarsdottir U; Zhou Y; Smith AV; Zhao JH; Amin N; Vedantam S; Shin SY; Haritunians T; Fu M; Feitosa MF; Kumari M; Halldorsson BV; Tikkanen E; Mangino M; Hayward C; Song C; Arnold AM; Aulchenko YS; Oostra BA; Campbell H; Cupples LA; Davis KE; Döring A; Eiriksdottir G; Estrada K; Fernández-Real JM; Garcia M; Gieger C; Glazer NL; Guiducci C; Hofman A; Humphries SE; Isomaa B; Jacobs LC; Jula A; Karasik D; Karlsson MK; Khaw KT; Kim LJ; Kivimäki M; Klopp N; Kühnel B; Kuusisto J; Liu Y; Ljunggren O; Lorentzon M; Luben RN; McKnight B; Mellström D; Mitchell BD; Mooser V; Moreno JM; Männistö S; O'Connell JR; Pascoe L; Peltonen L; Peral B; Perola M; Psaty BM; Salomaa V; Savage DB; Semple RK; Skaric-Juric T; Sigurdsson G; Song KS; Spector TD; Syvänen AC; Talmud PJ; Thorleifsson G; Thorsteinsdottir U; Uitterlinden AG; van Duijn CM; Vidal-Puig A; Wild SH; Wright AF; Clegg DJ; Schadt E; Wilson JF; Rudan I; Ripatti S; Borecki IB; Shuldiner AR; Ingelsson E; Jansson JO; Kaplan RC; Gudnason V; Harris TB; Groop L; Kiel DP; Rivadeneira F; Walker M; Barroso I; Vollenweider P; Waeber G; Chambers JC; Kooner JS; Soranzo N; Hirschhorn JN; Stefansson K; Wichmann HE; Ohlsson C; O'Rahilly S; Wareham NJ; Speliotes EK; Fox CS; Laakso M; Loos RJ. (Aug 2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet. 43:753-760. DOI.
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  • Chambers JC; Zhang W; Lord GM; van der Harst P; Lawlor DA; Sehmi JS; Gale DP; Wass MN; et alAhmadi KR; Bakker SJ; Beckmann J; Bilo HJ; Bochud M; Brown MJ; Caulfield MJ; Connell JM; Cook HT; Cotlarciuc I; Davey Smith G; de Silva R; Deng G; Devuyst O; Dikkeschei LD; Dimkovic N; Dockrell M; Dominiczak A; Ebrahim S; Eggermann T; Farrall M; Ferrucci L; Floege J; Forouhi NG; Gansevoort RT; Han X; Hedblad B; Homan van der Heide JJ; Hepkema BG; Hernandez-Fuentes M; Hypponen E; Johnson T; de Jong PE; Kleefstra N; Lagou V; Lapsley M; Li Y; Loos RJ; Luan J; Luttropp K; Maréchal C; Melander O; Munroe PB; Nordfors L; Parsa A; Peltonen L; Penninx BW; Perucha E; Pouta A; Prokopenko I; Roderick PJ; Ruokonen A; Samani NJ; Sanna S; Schalling M; Schlessinger D; Schlieper G; Seelen MA; Shuldiner AR; Sjögren M; Smit JH; Snieder H; Soranzo N; Spector TD; Stenvinkel P; Sternberg MJ; Swaminathan R; Tanaka T; Ubink-Veltmaat LJ; Uda M; Vollenweider P; Wallace C; Waterworth D; Zerres K; Waeber G; Wareham NJ; Maxwell PH; McCarthy MI; Jarvelin MR; Mooser V; Abecasis GR; Lightstone L; Scott J; Navis G; Elliott P; Kooner JS. (May 2010). Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 42:373-375. DOI.
  • Chahal NS; Lim TK; Jain P; Chambers JC; Kooner JS; Senior R. (Mar 2010). Ethnicity-related differences in left ventricular function, structure and geometry: a population study of UK Indian Asian and European white subjects. Heart. 96:466-471. DOI.
  • Sen-Chowdhry S; Morgan RD; Chambers JC; McKenna WJ. (2010). Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment. Annu Rev Med. 61:233-253. DOI.
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  • Williams ED; Steptoe A; Chambers JC; Kooner JS. (Dec 2009). Psychosocial risk factors for coronary heart disease in UK South Asian men and women. J EPIDEMIOL COMMUN H. 63:986-991. DOI.
  • Chahal NS; Lim TK; Jain P; Chambers JC; Kooner JS; Senior R. (Mar 2010). New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects. Eur Heart J. 31:588-594. DOI.
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  • Chahal NS; Lim TK; Jain P; Chambers JC; Kooner JS; Senior R. (Jan 2010). Normative reference values for the tissue Doppler imaging parameters of left ventricular function: a population-based study. Eur J Echocardiogr. 11:51-56. DOI.
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  • Chambers JC; Wander GS; Kooner JS. (Nov 2000). Homocysteine and coronary heart disease amongst Indian Asians. Indian Heart J. 52:S5-S8.
  • Chambers JC; Ireland H; Thompson E; Reilly P; Obeid OA; Refsum H; Ueland P; Lane DA; et alKooner JS. (Nov 2000). Methylenetetrahydrofolate reductase 677 C-->T mutation and coronary heart disease risk in UK Indian Asians. Arterioscler Thromb Vasc Biol. 20:2448-2452.
  • Rajkumar C; Aziz O; Chambers J; Kooner J; Bulpitt C. (2000). Does acute hyperhomocysteinaemia alter arterial compliance?. J HYPERTENS. 18:S195-S195.
  • Chambers JC; Obeid OA; Refsum H; Ueland P; Hackett D; Hooper J; Turner RM; Thompson SG; et alKooner JS. (12 Feb 2000). Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men. Lancet. 355:523-527. DOI.
  • Chambers JC; Obeid OA; Kooner JS. (Dec 1999). Physiological increments in plasma homocysteine induce vascular endothelial dysfunction in normal human subjects. Arterioscler Thromb Vasc Biol. 19:2922-2927.
  • Chambers JC; McGregor A; Jean-Marie J; Kooner JS. (May 1999). Abnormalities of vascular endothelial function may contribute to increased coronary heart disease risk in UK Indian Asians. Heart. 81:501-504.
  • Chambers JC; McGregor A; Jean-Marie J; Obeid OA; Kooner JS. (9 Mar 1999). Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation. 99:1156-1160.
  • Vakalopoulou S; Gooding R; Manning R; Eyre J; Chambers J; Kooner J; Laffan M. (May 1998). The effects of acute hyperhomocysteinaemia on platelet activation and PAI-1. BRIT J HAEMATOL. 101:82-82.
  • Michie CA; Chambers J; Abramsky L; Kooner JS. (11 Apr 1998). Folate deficiency, neural tube defects, and cardiac disease in UK Indians and Pakistanis. LANCET. 351:1105-1105.
  • Chambers JC; McGregor A; Jean-Marie J; Kooner JS. (3 Jan 1998). Acute hyperhomocysteinaemia and endothelial dysfunction. LANCET. 351:36-37.
  • Chambers JC; Somerville J; Stone S; Ross DN. (7 Oct 1997). Pulmonary autograft procedure for aortic valve disease: long-term results of the pioneer series. Circulation. 96:2206-2214.

Conferences

  • Sen-Chowdhry S; Syrris P; Pantazis A; Quarta G; Chambers JC; Mckenna WJ. Mutational heterogeneity, modifier genes, and environmental factors contribute to phenotypic variation in arrhythmogenic cardiomyopathy. 31:336-336. (Sep 2010).
  • Chahal N; Lim TK; Melderis S; Jain P; Chambers JC; Kooner JS; Senior R. INCREASED CAROTID ARTERY PLAQUE BURDEN IS ASSOCIATED WITH REDUCED SYSTOLIC LEFT VENTRICULAR FUNCTION AND INCREASED FILLING PRESSURE IN ASYMPTOMATIC INDIVIDUALS. 96:A65-A66. (Jun 2010). DOI.
  • Chahal NS; Lim TK; Meldris S; Jain P; Chambers JC; Kooner JS; Senior R. Increased Carotid Artery Plaque Burden is Associated With Reduced Left Ventricular Function in Asymptomatic Individuals. 120:S377-S377. (3 Nov 2009).
  • Chahal NS; Lim TK; Jain P; Chambers JC; Kooner JS; Senior R. ABNORMAL GEOMETRY IS ASSOCIATED WITH MORE SEVERE LEFT VENTRICULAR DYSFUNCTION IN THE PRESENCE OF INCREASED LEFT VENTRICULAR MASS: A POPULATION STUDY. 95:A75-A76. (Jun 2009).
  • Chambers JC; Zhang W; Sehmi J; Jain P; Scott J; Elliott P; Kooner JS. COMMON GENETIC VARIATION NEAR MTNR1B CONTRIBUTES TO RAISED PLASMA GLUCOSE AND INCREASED RISK OF TYPE-2 DIABETES AMONG INDIAN ASIANS. 95:A82-A82. (Jun 2009).
  • Sehmi JS; Rai BK; Chambers JC; Kooner JS. DO COMMON GENETIC VARIANTS IN FTO AND MC4R INFLUENCE WEIGHT CHANGE FOLLOWING DIETARY INTERVENTION. 95:A62-A62. (Jun 2009).
  • McHale E; Ahmed N; Sehmi J; Kooner JS; Chambers JC. DOES LEFT VIENTRICULAR HYPERTROPHY IDENTIFY THE INCREASED RISK OF CORONARY HEART DISEASE AMONG UK INDIAN ASIANS?. 95:A33-A34. (Jun 2009).
  • Elliott P; Chambers JC; Zhang W; Clarke R; Peden JF; Erdmann J; Braund P; Engert J; et alHopewell J; Coin L; Ashby D; McCarthy MI; Farrall M; Jarvelin MR; Scott J; Hall AS; Schunkert H; Anand SS; Collins R; Samani N; Watkins H; Kooner JS. GENETIC LOCI INFLUENCING C-REACTIVE PROTEIN LEVELS AND CORONARY HEART DISEASE RISK: RESULTS OF GENETIC ASSOCIATION AND MENDELIAN RANDOMISATION STUDY WITH META-ANALYSIS IN 80 614 PEOPLE. 95:A61-A61. (Jun 2009).
  • Chahal N; Lim TK; Jain P; Chambers JC; Kooner JS; Senior R. Abnormal Geometry With Increased Left Ventricular Mass and Not Concentric Remodelling Is Associated With Abnormal Left Ventricular Function in Hypertensives: A Population Study. 53:A212-A213. (10 Mar 2009).
  • Parkes J; Harris S; Lightstone E; Chambers J; Kooner J; Roderick P. RAISED ALT IS ASSOCIATED WITH ETHNICITY IN A LARGE GENERAL POPULATION COHORT IN LONDON UK (LOLIPOP STUDY). 50:S368-S368. (2009).
  • Chambers J; Elliott P; Zhang WH; Keener JS. Contribution Of Known Genetic Factors To Increased Risk Of Type-2 Diabetes In Indian Asians. 118:S1117-S1117. (28 Oct 2008).
  • Chambers J; Elliott P; Zhang WH; Samani N; Kooner JS. Do Known Genetic Factors Contribute to the Increased Risk of Cardiovascular Disease Amongst Indian Asians?. 118:S1101-S1101. (28 Oct 2008).
  • Zhang W; Zabaneh D; Balding D; McCarthy MI; Elliott P; Scott J; Kooner JS; Chambers JC. Are Indian Asians genetically homogeneous? Implications for genetic association studies. 94:A65-A65. (Jul 2008).
  • Chahal NS; Lim TK; Jain P; Chambers JC; Senior R; Kooner JS. Carotid intima-media thickness as a surrogate marker of atherosclerosis and cardiovascular disease risk in healthy UK Indian Asians and European whites. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A8-A9. (Jul 2008).
  • Jain P; Chambers JC; Elliott P; Williams ED; Kraly B; Muscat S; Lahiri A; Kooner JS. Coronary artery calcification as a predictor of increased coronary heart disease risk in UK Indian Asians. 94:A77-A77. (Jul 2008).
  • Chambers JC; Zhang W; Zabaneh D; Balding D; McCarthy MI; Scott J; Elliott P; Kooner JS. Does genetic variation in FTO account for the increased risk of obesity and type 2 diabetes in UK Indian Asians?. 94:A58-A59. (Jul 2008).
  • Chambers JC; Elliott P; Scott J; Kooner JS. Genome-wide association study identifies mlxipl as a novel determinant of trigyceride levels in man. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A5-A5. (Jul 2008).
  • Sehmi JS; Chambers JC; Kooner JS. Inflammatory processes are associated with insulin resistance among UK Indian Asians, and not accounted for by obesity. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A38-A39. (Jul 2008).
  • Chambers JC; Scott J; Meeran K; Jain P; Bloom S; Kooner JS. Transcription factor 7-like 2, insulin action and risk of type 2 diabetes among Indian Asian and White European men. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A59-A59. (Jul 2008).
  • Chambers JC; Scott J; Hinds DA; Fraser KA; Warnes GR; Aguilar-Salinas C; Hyde C; Milos PM; et alThompson JF; Cox DR; Kooner JS. A genome-wide scan identifies novel and known DNA variants associated with component phenotypes of metabolic syndrome. 116:507-507. (16 Oct 2007).
  • Alakakone A; Tillin T; Chambers J; Malik I; Coady E; Raynor S; Mayet J; Wright A; et alKooner J; Shore A; Thom S; Chaturvedi N; Hughes A. Do differences in lower limb blood flow explain the ethnic disparity in peripheral arterial disease incidence between South Asians and Europeans?. 50:803-803. (Oct 2007).
  • Zabaneh D; Chambers JC; Elliott P; Baliga R; Scott J; Balding DJ; Kooner JS. Estimating heritabilities and genetic correlations of insulin resistance and related metabolic traits in Indian families using a multivariate maximum likelihood approach. 31:651-651. (Sep 2007).
  • Lim TK; Lim E; Jain P; Chambers JC; Elliott P; Kooner J; Senior R. Investigation of the relationship between type 2 diabetes and left ventricular function in men and women aged 35-75 years. 79th Annual Scientific Session of the American-Heart-Association. 114:895-895. (31 Oct 2006).
  • Chambers JC; Elliott P; Scott J; Kooner JS. Obesity and risk of Type 2 diabetes in UK Indian Asians and Northern Europeans in the London Life Sciences Population (LOLIPOP) Study. 79th Annual Scientific Session of the American-Heart-Association. 114:854-854. (31 Oct 2006).
  • Chambers JC; Elliott P; Scott J; Kooner JS. Physical activity and risk of type 2 diabetes in UK Indian Asian and Northern European subjects in the London Life Sciences Population (LOLIPOP) study. 79th Annual Scientific Session of the American-Heart-Association. 114:894-895. (31 Oct 2006).
  • Chambers JC; Lim E; Elliott P; Scott J; Kooner JS. The age and gender related patterns of insulin resistance in UK Indian Asians and Northern Europeans: The London Life Sciences Population (LOLIPOP) Study. 79th Annual Scientific Session of the American-Heart-Association. 114:902-903. (31 Oct 2006).
  • Chambers JC; Frazer KA; Hinds DA; Milos PM; Cox DR; Thompson JF; Scott J; Kooner JS. Transcription factor 7-like-2 polymorphisms and risk of type 2 diabetes in Indian Asians and Northern Europeans. 79th Annual Scientific Session of the American-Heart-Association. 114:888-888. (31 Oct 2006).
  • Tillin T; Dhutia H; Chambers J; Malik I; Coady E; Mayet J; Wright A; Kooner J; et alChaturvedi N; Hughes A. British South Asian men have more adverse plaque morphology despite equivalent atherosclerotic burden to White Europeans. 7:80-80. (Jun 2006).
  • Tillin T; Dhutia H; Chambers J; Malik I; Coady E; Mayet J; Wright A; Kooner J; et alChaturvedi N; Hughes A. South Asians have narrower coronary arteries and different remodelling responses to disease compared to white Europeans. 7:80-80. (Jun 2006).
  • Lim E; Lightstone L; Chambers J; Roderick P; Mullee M; Kooner J. Chronic kidney disease as a cardiovascular risk factor in UK Indian Asians compared to UK Northern Europeans: The London Life Sciences Prospective Population Study (LOLIPOP). 92:A12-A12. (May 2006).
  • Chambers J; Lim E; Singh D; Jain P; Elliott P; Kooner J. Investigation of cardiovascular risk factors among UK Indian Asians and European whites: The London Life Sciences Population (LOLIPOP) Study. 92:A12-A12. (May 2006).
  • Chambers J; Lim E; Jain P; Singh D; Elliott P; Kooner J. The age and gender related prevalence of the metabolic syndrome among UK Indian Asians and European whites: First results from the London Life Sciences Population (LOLIPOP) Study. 92:A11-A12. (May 2006).
  • Chambers JC; Wander GS; Hooper J; Anand IS; Kooner JS. Plasma homocysteine and coronary heart disease mortality in India. 89:A58-A58. (May 2003).
  • Chambers JC; Anand IS; Wander GS; Kooner JS. Plasma homocysteine and coronary heart disease mortality in India. 106:732-733. (5 Nov 2002).
  • Chambers JC. Homocysteine: a reversible risk factor for coronary heart disease. EMBODY 2000 Conference. 374-378. (2002).
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