Microbial Pathogenesis example projects
Below are some examples of previous project titles made available for students who chose the Microbial Pathogenesis stream within the MRes in Biomedical Research. Please note that these are just for your reference, and availability of projects is subject to change each year.
- Structure/function analysis of ComP, a DNA-binding protein key for DNA transformation in the human pathogen Neisseria meningitidis
- Structural and functional characterization of Mycobacterium tuberculosis proteins PE13/PPE18
- Identify and investigate cellular targets of c-di-AMP in Staphylococcus aureus
- The role of PPE_MPTR proteins in host-pathogen interactions
- The role of capsule in Acinetobacter baumannii pathogenesis
- Menigococcal Type four pili (Tfp)
- Investigation into the phosphorylation state of the mycobacterial response regulator GlnR under nitrogen stress
- Genome wide screen to identify bacterial proteins that interact with Lipoteichoic acid synthesis proteins
- Antifungals, Sterols, Oxidative Stress and Candida glabrata
- Cloning and Expression of Nosema ceranae Secreted Proteins
- Use of bioluminescence reporters to study mycobacterial gene expression in vitro and during macrophage infection
- Role of the sodium-ATPase Ena1 in A. fumigatus virulence
- Dissecting the function of a subtelomeric gene cluster induced during A. fumigatus host-adaptation
- Measuring cytosolic calcium in the mould pathogen Aspergillus fumigatus
- Involvement of the transcription factor SltA in vacuole biogenesis and trafficking in the fungal model Aspergillus nidulans, an occasional pathogen
- Preventing alkaline adaptation in pathogenic fungi: a novel transcription factor supporting cation homeostasis and filamentous growth
- Transcriptional regulation of the agr operon in Staphylococcus aureus
- Transcriptional regulation and the fungal pathogenicitydetermining ambient pH response: members of the genome controlled by ambient pH
- Role of Base Excision Repair in Meningococcal Pathogenesis
- Analysis of Intracellular Replication by Shigella flexneri
Details about the research projects available in the upcoming year are made available upon starting the course.
