Papers 2003

Publications 2003

Bergamaschi D, Gasco M, Hiller L, Sullivan A, Syed N, Trigiante G, Yulug I, Merlano M, Numico G, Comino A, Attard M, Gusterson B, K Bell AK, Heath V, Tavassoli M, Farrell PJ, Smith P, Lu X and Crook T. p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell 3: 387-402, 2003.

Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X. iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human. Nature Genetics. 33: 162-167, 2003.

Carter, G., Rodger, G., Law, M., Murphy, B.J., Hollinshead, M., Krauss, O., & Smith, G.L. (2003). Vaccinia virus cores are transported on microtubules. J. Gen. Virol. 84, 2443-2458.

de Jesus O, Smith PR, Spender L, Elgueta Karstegl C, Niller HH, Huang D and Farrell PJ. Updated Epstein-Barr virus DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of Epstein-Barr virus. J. Gen. Virol. 84: 1443-1450, 2003.

Gasco M and Crook T. The p53 network in head and neck cancer. Oral Oncology 39: 222-231, 2003.

Gasco M and Crook T. p53 family members and chemoresistance in cancer: what we know and what we need to know.  Drug Resistance Updates,  6: 323-328, 2003.

Gasco M, Yulug IG and Crook T. TP53 mutations in familial breast cancer: functional aspects. Human Mutation. 21: 301-306, 2003.

Harte, M.T., Haga, I., Maloney, G., Gray, P., Reading, P.C., Bartlett, N., Smith, G.L., Bowie, A. & O’Neill, L. (2003). The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defence. J. Exp. Med. 197, 343-351.

Joaquin M and Watson RJ.  The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57Kip2 by interacting with its cyclin-binding domain.  J. Biol. Chem. 278: 44255-44264,  2003.

Joaquin M and Watson RJ. Cell cycle regulation by the B-Myb transcription factor.  Cell Mol Life Sci. 60: 2389-2401, 2003.

McConkey, S. J., Reece, W. H., Moorthy, V. S., Webster, D., Dunachie, S., Butcher, G., Vuola, J.M., Blanchard, T.J., Gothard, P., Watkins, K., Hannan, C.M., Everaere, S., Brown, K., Kester, K.E., Cummings, J., Williams, J., Heppner, D.G., Pathan, A., Flanagan, K., Arulanantham, N., Roberts, M.T., Roy, M., Smith, G.L., Schneider, J., Peto, T., Sinden, R.E., Gilbert, S.C. Hill, A.V. (2003). Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nature Med. 9, 729-35.

Melino G, Lu X, Gasco M, Crook T and Knight RA. Complexities in the functional regulation of p63 and p73: from development to cancer?  Trends in Biological Sciences 28: 663-670, 2003

Najarro, P., Lee, H.-J., Fox, J., Pease, J. & Smith, G.L. (2003). Yaba-like disease virus protein 7L is a cell surface receptor for chemokine CCL1. J. Gen. Virol. 84, 3325-3336.

O'Nions, J. and Allday M.J.  Epstein-Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2.  Oncogene 22: 7181-7191 , 2003.

Osin P, Lu Y-J, Stone J, Crook T, Houlston RS, Gasco M, Gusterson BA and Shipley J. Distinct genetic and epigenetic changes in medullary breast cancer. Int. J. Surg. Pathol., 11: 153-158, 2003.

Pires de Miranda, M., Reading, P.C., Tscharke, D.C., Murphy, B.J. & Smith, G.L. (2003). The vaccinia virus kelch-like protein C2L affects calcium-independent adhesion to the extracellular matrix and inflammation in a murine intradermal model. J. Gen. Virol. 84, 2459-2471.

Reading, P.C., Moore, J.B. & Smith, G.L. (2003). Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection. J. Exp. Med. 197, 1269-1278

Reading, P.C. & Smith, G.L. (2003). A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. J. Gen. Virol. 84, 1973-1983.

Reading, P.C. & Smith, G.L. (2003). Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer cell and T cell activity. J. Virol. 77, 9960-9968.

Reading, P.C., Symons, J.A. & Smith, G.L. (2003). A soluble chemokine-binding protein from vaccinia virus reduces virulence and the inflammatory response to infection. J. Immunol. 170, 1435-1442.

Renton A, Llanos S and Lu X. Hypoxia induces p53 through a pathway distinct from most DNA-damaging and stress-inducing agents.  Carcinogenesis. 24:1177-1182, 2003.

Smith, G.L., Murphy, B.J. & Law, M. (2003). Vaccinia virus motility. Annu. Rev. Microbiol. 57, 323-342.

Slee EA and Lu X.  The ASPP family: deciding between life and death after DNA damage. Toxicol Lett. 139:81-87, 2003.