Division of Infectious Diseases
The Division of Infectious Diseases is led by Professor Charles Bangham and is subdivided into six sections:
Sections
Immunology Section
Immunology at St Mary's is led by Professor Charles Bangham. There are three principal research themes in the Section: i. virology, immunology and dynamics of infection with the human leukaemia virus, HTLV-1. ii. MHC Class I antigen presentation. iii. Leishmania infection.
- Immunology at Chelsea and Westminster is led of Professor Frances Gotch and investigates primary and secondary immunodeficiencies.In addition this site also houses the Human Immunology Laboratory (HIL) for the International AIDS Vaccine Initiative (IAVI) - which run by Jill Gilmour, Peter Hayes and Tony Tarragona-Fiol.
- Immunology at Northwick Park is led by Professor Stella Knight - the laboratories of her Antigen Presentation Research Group have become established as the major research facility for St. Mark’s Hospital and Institute of Colorectal Diseases. The APRG studies human Mucosal Immunity, and Nutrition and Immunity, identifying mechanisms by which dendritic cells perform the dual roles of either initiating or blocking the development of immunity.
Infectious Diseases
Headed by Prof Myra McClure and incorporates the following groups:
- HIV clinical trials led by Prof Jonathan Weber
- CD4 Initiative led by Dr Hans-Georg Batz
- Wellcome Centre for Clinical Tropical Medicine led by Geoffrey Pasvol
- Retrovirology - led by Professor Myra McClure
- Molecular Diagnostic Unit - led by Myra McClure and managed by Drs Graham Taylor and Steve Kaye
- Glycobiology - led by Professor Ten Feizi
- Mucosal Infection and Immunity - led by Professor Robin Shattock
- Imperial Vaccine Partnership - led by Professor Robin Shattock
Infectious Diseases and Immunity
Based at Hammersmith Hospital Is led by Professor Jon Friedland and its research interests range from tuberculosis through novel approaches in drug discovery to gram positive sepsis and hospital acquired infection.
- This section also incorporates the Centre for Infection Prevention and Management which is Co-directed by Professors Jon Freidland and Alison Holmes
Microbiology
Is based at South Kensington Campus and is led by Professor David Holden.
- The section has two major research themes centred around microbial pathogenicity and environment sensing. Microbiology is also closely integrated with the Centre for Molecular Microbiology And Infection (CMMI) which is a joint initiative with the Faculty of Natural Sciences. The overall goals of the CMMI are to understand the biology of infectious diseases with an emphasis on bacterial infections, and to translate this information into novel strategies for preventing and treating microbial disease.
Paediatrics
Is largely based at St Mary's Campus and led by Professor John Warner. The research interests of the section are:
- Allergy and infectious diseases in particular has facilitated research into tuberculosis with or without HIV, and investigation of immune dysfunction in malnourished children.
- Community health - focuses on child public health and population paediatrics, behavioural and developmental paediatrics, neurodisability , social paediatrics and child protection, ambulatory paediatrics
- Neonatal medicine - investigates the impact that care during the neonatal period has for adult health and wellbeing. Our research encompasses the understanding of fundamental processes during normal development - with particular reference to the regulation of body composition, multi-centre clinical trials and population based epidemiology
Virology
Based at St Mary's Campus the Section and is led by Prof Paul Farrell:
- The Section plays a leading role in research in virology, cell biology and immunology. Virology undergraduate teaching is also provided by this Section. Its main areas of interest are calicivirus, cell cycle control, Epstein-Barr virus, hepesvirus assembly, influenza, oncogenic herpesviruses, , vaccine vector and the imaging Centre.
